Neobotanics Vitamin D3 + K2 liquid supplement in sea buckthorn oil with vitamins 50 ml (1750 doses)

980 Kč
3 reviews

Immune system and defense

Family pack - 1750 daily doses in a bottle. Liquid form of a high dose of vitamins D and K. Vitamin D contributes to the normal function of the immune system, vitamin K contributes to the maintenance of normal bone condition.

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Ingredients

MCT oil (medium chain triglycerides), sea buckthorn oil (7%), antioxidant: vitamin E (D-alpha-tocopheryl acetate), antioxidant: rosemary extract, cholecalciferol (vitamin D), menaquinone-7 (vitamin K).

It does not contain any dyes, flavors, binders, thickeners, anti-caking agents or flavor enhancers.

The package contains approximately 1750 drops (1,750,000 IU of vitamin D and 43,750 ug of vitamin K).

How to use

RECOMMENDED DOSAGE:

1 drop daily. 1 drop contains 1000 IU (25 g, 500% RDI*) of vitamin D3 and 25 g (33.3% RDI*) of vitamin K2-MK7. *RDI = reference intake value).


NOTICE:

Do not exceed the recommended daily dose. Not intended as a substitute for a varied and balanced diet. Not suitable for children, pregnant and lactating women.



STORAGE:

Do not exceed the recommended daily dose. Not intended as a substitute for a varied and balanced diet. Not intended for children, pregnant or breastfeeding women. Keep out of reach of children, protect from direct sunlight. After opening, keep refrigerated and consume within 6 months.



References and studies:

1 Grant WB, Lahore H, McDonnell SL, Baggerly CA, French CB, Aliano JL, Bhattoa HP. Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths. Nutrients. 2020 Apr 2;12(4):988.
2 Holick MF. Vitamin D deficiency. N Engl J Med. 2007 Jul 19;357(3):266-81.
3 Linnebur SA, Vondracek SF, Vande Griend JP, Ruscin JM, McDermott MT. Prevalence of vitamin D insufficiency in elderly ambulatory outpatients in Denver, Colorado. Am J Geriatric Pharmacother. 2007 Mar;5(1):1-8.
4 Vitamin K as a Diet Supplement with Impact in Human Health: Current Evidence in Age-Related Diseases
Dina C. Simes, Carla SB Viegas, Nuna Araújo, Catarina Marreiros. Nutrients. 2020 Jan; 12(1): 138.
5 Goddek S. Vitamin D3 and K2 and their potential contribution to reducing the COVID-19 mortality rate. Int J Infect Dis. 2020 Oct;99:286-290.
6 Kidd PM. Vitamins D and K as pleiotropic nutrients: clinical importance to the skeletal and cardiovascular systems and preliminary evidence for synergy. Altern Med Rev. 2010 Sep;15(3):199-222.
7 Iwamoto J, Takeda T, Ichimura S. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis. J Orthop Sci. 2000;5(6):546-51.
8 Aguayo-Ruiz JI, García-Cobián TA, Pascoe-González S, Sánchez-Enríquez S, Llamas-Covarrubias IM, García-Iglesias T, López-Quintero A, Llamas-Covarrubias MA, Trujillo-Quiroz J, Rivera-Leon EA. Effect of supplementation with vitamins D3 and K2 on undercarboxylated osteocalcin and insulin serum levels in patients with type 2 diabetes mellitus: a randomized, double-blind, clinical trial. Diabetol Metab Syndr. 2020 Aug 18;12:73.
9 Iwamoto J, Takeda T, Ichimura S. Treatment with vitamin D3 and/or vitamin K2 for postmenopausal osteoporosis. Keio J Med. 2003 Sep;52(3):147-50.

In stock

Product information

The NEOBOTANICS® brand

NEOBOTANICS® was founded on the basis of long-term scientific research into natural bioactive substances under the leadership of Associate Professor Petr Kaštánek, Ph.D., in cooperation with prominent Czech scientific institutions and leading experts in the field of medicine.

From the very beginning, we have been building on the conviction that truly valuable skin care and sophisticated dietary supplements should grow from a deep understanding of nature, precise research and high demands on the quality of each ingredient used.

 

BIOCEN laboratories

Research, development and production take place under strictly controlled conditions in the laboratories of our company BIOCEN laboratories and our laboratories in the Science and Technology Park Dobříš Centre for Applied Research (CAVD), set in the unique environment of the Brdy forests.

It is here that scientific precision, technological advancement and inspiration from nature, which is fundamental to the philosophy of the NEOBOTANICS® brand, are intertwined.

 

Associate Professor Petr Kaštánek, Ph.D.,

The founder of the NEOBOTANICS® brand is a Czech scientist and biotechnologist specializing in the entire chain of research, development and utilization of natural bioactive substances.

Within the research projects he leads, new active ingredients for cosmetic use and new approaches to their formulation are developed.

He is the holder of a number of patents and awards, including the Visionary 2016 title.

More about Petr HERE.

View our Research Projects

In-house research and development

Our passion and expertise lie in developing high-quality products with well-thought-out compositions, offering sophisticated and functional skin care.

We emphasize careful selection of raw materials, balanced formulations, safety of use, and respect for sustainability and environmental protection. Each product is created with the aim of offering modern care that combines a scientific approach, attention to detail, and a high standard of quality.
At the heart of the company is the laboratory — a place where innovative ideas are born, new procedures are verified, and products are created that connect research, functionality, and a refined approach to modern care.

Combining modern science, research, and nature

We believe that the future of quality cosmetics and dietary supplements relies not only on the latest scientific knowledge but also on a sensitive connection to natural traditions.
Therefore, we return to our roots and rediscover the potential of traditional and lesser-known local herbs, plants, and other natural resources for use in dermatology, cosmetics, and nutrition.
These resources are explored through research projects led by the founder of the NEOBOTANICS® brand, biotechnologist and expert in natural active substances, doc. Ing. Petr Kaštánek, Ph.D. We extract valuable functional ingredients from them and verify their biological activity using modern analytical methods.

Bioactive, thoughtfully formulated ingredients

In many of our dietary supplements and cosmetic products, we use our own original and carefully prepared extracts.
Where appropriate for formulation, we work with bioactive substances in the form of liposomal or nano-micellar systems, prepared using our own NEOLIPO® and NEOMICELLE® processes.
These approaches allow us to design products with an emphasis on stability, quality, and a thoughtful use of active ingredients within the overall formulation.

Extreme origin, exceptional potential

In the development of dermo-cosmetic products, we also work with bioactive substances obtained from plants or microorganisms that naturally occur in extreme conditions.
It is precisely in such environments that these organisms create specific protective mechanisms and a natural spectrum of substances that help them cope with environmental stressors.
This unique natural origin is a valuable inspiration for us in creating products designed for modern, functional, and targeted skin care.

Double synergy

The philosophy of the NEOBOTANICS® brand, alongside scientific development inspired by natural bioactive substances, is also based on the principle of so-called double synergy.
The first level is the thoughtful combination of individual active ingredients within each product so that they together create a harmonious and functional whole.
The second level is the connection between external and internal care — that is, between dermo-cosmetics and carefully formulated dietary supplements within the broad NEOBOTANICS® portfolio.
It is precisely this comprehensive approach that characterizes our brand: science, nature, and thoughtful care in a refined, modern, and premium form.

Shipping Czech Republic:
  • DPD Private (option to change date or address): 75 CZK
  • Zásilkovna pick-up point or Z-box (selection after completing the order): 69.00 CZK
  • Zásilkovna home delivery (selection after completing the order): 99.00 CZK

FREE shipping for orders over 2,000 CZK (applies only to orders within the Czech Republic).

Payment options:
  • Card online (instant transfer) free
  • Bank transfer (transfer 1-2 days) free
  • Cash on delivery (payment upon receipt): 30 CZK

Payment method providers: ComGate, Viva Payment

In case of cashless payment, the purchase price is due within 7 days from the conclusion of the purchase agreement.

Delivery time:
  • within 2-3 business days for online card payment and cash on delivery
  • within 2-4 business days for bank transfer payment

Questions regarding shipping and payment should be addressed to info@neobotanics.cz or by phone at +420 776 187 414

Shipping outside the Czech Republic:

Austria

AUS Home delivery HD (Orders 0kg–5kg): €10.00 /220 CZK

Belgium

Belgian Post HD (Orders 0kg–5kg): €11.00 /270 CZK
Belgian Post PP (Orders 0kg–5kg): €11.00 /270 CZK

France

FR Colissimo HD (Orders 0kg–5kg): €15.00 /350 CZK
FR Colissimo PP (Orders 0kg–5kg): €15.00 /350 CZK

Germany

DE Hermes HD (Orders 0kg–10kg): €8.00 /180 CZK

DE Home delivery HD (Orders 0kg–10kg): €9.00 /200 CZK

Hungary

HU Home delivery (Orders 0kg–5kg): Ft2,368.00 /170 CZK

Italy

IT Bartolini HD (Orders 0kg–5kg): €10.00 /220 CZK

IT HR Parcel HD(Orders 0kg–5kg): €10.00 /220 CZK

Poland

PL Home delivery HD (Orders 0kg–5kg): PLN 30.00 /170 CZK

PL Packeta Z-Point PP (Orders 0kg–5kg): PLN 30.00 /170 CZK

Portugal

PT MRW HD (Orders 0kg–5kg): €10.00 /220 CZK

PT MRW PP (Orders 0kg–5kg): €10.00 /220 CZK

Slovakia

SK Packeta delivery HD (Orders 0kg–5kg): €6.00 /130 CZK

SK Packeta evening delivery HD (Orders 0kg–5kg): €7.00 /160 CZK

SK Z-Box Box (Orders 0kg–5kg): €4.00 /95 CZK

SK Zásilkovna * You select the Zásilkovna branch after completing the order (Orders 0kg–5kg): €4.00 /95 CZK

Payment options:

  • Bank transfer (transfer 1-2 days) free
  • Card online (instant transfer) free
  • CAUTION: Cash on delivery is not possible for shipping outside the Czech Republic!
Payment method providers: ComGate, Viva PaymentIn case of cashless payment, the purchase price is due within 7 days from the conclusion of the purchase agreement.

Delivery time:
  • within 2-3 business days for card payment
  • within 3-4 business days from the crediting of the amount to the account for bank transfer payment

 

Questions regarding shipping and payment should be addressed to info@neobotanics.cz or by phone at +420 776 187 414

Neobotanics Vitamin D3 + K2 liquid supplement in sea buckthorn oil with vitamins 50 ml (1750 doses)

Liquid form of a high dose of vitamins D and K. Vitamin D contributes to the normal function of the immune system, vitamin K contributes to the maintenance of normal bone condition.

With added vitamin E and rosemary extract as antioxidants.
Strong formulation - in a daily dose (1 drop) contains 500% of the recommended daily intake of vitamin D and 33.3% of vitamin K. The bottle contains approximately 1750 daily doses. No added dyes or preservatives.


Vitamin D contributes to:

  • normal function of the immune system
  • maintaining normal bones and teeth
  • maintaining normal muscle function
  • normal absorption/utilization of calcium and phosphorus
  • normal blood calcium levels

Vitamin K contributes to:

  • normal blood clotting
  • maintaining normal bone condition


Expert studies show that it is advisable to combine vitamin D3 with vitamin K2.


The Czech population suffers from a deficiency of vitamin D. This is essential for the normal function of the immune system (1). Very few foods naturally contain or are enriched with vitamin D. People obtain it from exposure to sunlight, from a diet rich in fatty fish, or from medications and dietary supplements. It is estimated that up to 1 billion people worldwide may suffer from a vitamin D deficiency. Therefore, it is absolutely necessary to supplement vitamin D, whether in its natural form - the sun, fish, or in the form of artificial ones, i.e. medications and specialized dietary supplements.

Vitamin D deficiency affects a large part of the elderly population, especially women living in countries with a temperate climate, due to reduced vitamin D intake in the diet (mainly from the consumption of fatty marine fish). The lowest seasonal concentration of the active form of vitamin D is usually observed during winter and spring. It is particularly alarming that more than 50% of postmenopausal women taking osteoporosis medications have insufficient levels of the active form of vitamin D3 in their blood, as shown, for example, by a study by Boston University (2). A study conducted among outpatients in Denver showed vitamin D deficiency in as many as 74% of seniors aged 66-89 years (3).

Vitamin K2 is an expensive substance, but research shows that it is very important for the human body (4), especially for maintaining normal bone health. Its dietary sources are mainly beef, yogurt and soft cheeses. However, its intake in a typical Central European diet may not be sufficient. Some vitamin K2 is also produced by bacteria naturally present in the human intestine. However, their activity can be weakened in the case of frequent use of antibiotics.

A number of studies (5-9) show that there are synergistic (mutually reinforcing) effects of simultaneous administration of vitamins D and K.

Reference:

1 Grant WB, Lahore H, McDonnell SL, Baggerly CA, French CB, Aliano JL, Bhattoa HP. Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths. Nutrients. 2020 Apr 2;12(4):988.

2 Holick MF. Vitamin D deficiency. N Engl J Med. 2007 Jul 19;357(3):266-81.

3 Linnebur SA, Vondracek SF, Vande Griend JP, Ruscin JM, McDermott MT. Prevalence of vitamin D insufficiency in elderly ambulatory outpatients in Denver, Colorado. Am J Geriatric Pharmacother. 2007 Mar;5(1):1-8.

4 Vitamin K as a Diet Supplement with Impact in Human Health: Current Evidence in Age-Related Diseases

Dina C. Simes, Carla SB Viegas, Nuna Araújo, Catarina Marreiros. Nutrients. 2020 Jan; 12(1): 138.

5 Goddek S. Vitamin D3 and K2 and their potential contribution to reducing the COVID-19 mortality rate. Int J Infect Dis. 2020 Oct;99:286-290.

6 Kidd PM. Vitamins D and K as pleiotropic nutrients: clinical importance to the skeletal and cardiovascular systems and preliminary evidence for synergy. Altern Med Rev. 2010 Sep;15(3):199-222.

7 Iwamoto J, Takeda T, Ichimura S. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis. J Orthop Sci. 2000;5(6):546-51.

8 Aguayo-Ruiz JI, García-Cobián TA, Pascoe-González S, Sánchez-Enríquez S, Llamas-Covarrubias IM, García-Iglesias T, López-Quintero A, Llamas-Covarrubias MA, Trujillo-Quiroz J, Rivera-Leon EA. Effect of supplementation with vitamins D3 and K2 on undercarboxylated osteocalcin and insulin serum levels in patients with type 2 diabetes mellitus: a randomized, double-blind, clinical trial. Diabetol Metab Syndr. 2020 Aug 18;12:73.

9 Iwamoto J, Takeda T, Ichimura S. Treatment with vitamin D3 and/or vitamin K2 for postmenopausal osteoporosis. Keio J Med. 2003 Sep;52(3):147-50.

The NEOBOTANICS® brand

NEOBOTANICS® was founded on the basis of long-term scientific research into natural bioactive substances under the leadership of Associate Professor Petr Kaštánek, Ph.D., in cooperation with prominent Czech scientific institutions and leading experts in the field of medicine.

From the very beginning, we have been building on the conviction that truly valuable skin care and sophisticated dietary supplements should grow from a deep understanding of nature, precise research and high demands on the quality of each ingredient used.

 

BIOCEN laboratories

Research, development and production take place under strictly controlled conditions in the laboratories of our company BIOCEN laboratories and our laboratories in the Science and Technology Park Dobříš Centre for Applied Research (CAVD), set in the unique environment of the Brdy forests.

It is here that scientific precision, technological advancement and inspiration from nature, which is fundamental to the philosophy of the NEOBOTANICS® brand, are intertwined.

 

Associate Professor Petr Kaštánek, Ph.D.,

The founder of the NEOBOTANICS® brand is a Czech scientist and biotechnologist specializing in the entire chain of research, development and utilization of natural bioactive substances.

Within the research projects he leads, new active ingredients for cosmetic use and new approaches to their formulation are developed.

He is the holder of a number of patents and awards, including the Visionary 2016 title.

More about Petr HERE.

View our Research Projects

In-house research and development

Our passion and expertise lie in developing high-quality products with well-thought-out compositions, offering sophisticated and functional skin care.

We emphasize careful selection of raw materials, balanced formulations, safety of use, and respect for sustainability and environmental protection. Each product is created with the aim of offering modern care that combines a scientific approach, attention to detail, and a high standard of quality.
At the heart of the company is the laboratory — a place where innovative ideas are born, new procedures are verified, and products are created that connect research, functionality, and a refined approach to modern care.

Combining modern science, research, and nature

We believe that the future of quality cosmetics and dietary supplements relies not only on the latest scientific knowledge but also on a sensitive connection to natural traditions.
Therefore, we return to our roots and rediscover the potential of traditional and lesser-known local herbs, plants, and other natural resources for use in dermatology, cosmetics, and nutrition.
These resources are explored through research projects led by the founder of the NEOBOTANICS® brand, biotechnologist and expert in natural active substances, doc. Ing. Petr Kaštánek, Ph.D. We extract valuable functional ingredients from them and verify their biological activity using modern analytical methods.

Bioactive, thoughtfully formulated ingredients

In many of our dietary supplements and cosmetic products, we use our own original and carefully prepared extracts.
Where appropriate for formulation, we work with bioactive substances in the form of liposomal or nano-micellar systems, prepared using our own NEOLIPO® and NEOMICELLE® processes.
These approaches allow us to design products with an emphasis on stability, quality, and a thoughtful use of active ingredients within the overall formulation.

Extreme origin, exceptional potential

In the development of dermo-cosmetic products, we also work with bioactive substances obtained from plants or microorganisms that naturally occur in extreme conditions.
It is precisely in such environments that these organisms create specific protective mechanisms and a natural spectrum of substances that help them cope with environmental stressors.
This unique natural origin is a valuable inspiration for us in creating products designed for modern, functional, and targeted skin care.

Double synergy

The philosophy of the NEOBOTANICS® brand, alongside scientific development inspired by natural bioactive substances, is also based on the principle of so-called double synergy.
The first level is the thoughtful combination of individual active ingredients within each product so that they together create a harmonious and functional whole.
The second level is the connection between external and internal care — that is, between dermo-cosmetics and carefully formulated dietary supplements within the broad NEOBOTANICS® portfolio.
It is precisely this comprehensive approach that characterizes our brand: science, nature, and thoughtful care in a refined, modern, and premium form.