Neobotanics Anti-Wrinkle Skin Rejuvenator #1 anti-wrinkle serum with peptides, stem cells and hyaluronic acid 30 ml
Rapid wrinkle reduction, anti-aging, collagen reactivation
Ingredients
How to use
Product information
The NEOBOTANICS® brand was created on the basis of scientific research into natural bioactive substances, led by Doc. Prof. Ing. Petr Kaštánek, PhD., in cooperation with major Czech scientific institutions and top doctors.
Research, development and production take place under the strictest conditions in the laboratories of our parent company BIOCEN laboratories and in the Science and Technology Park of the Applied Research Center Dobříš (CAVD) in the midst of the beautiful landscape of the Brdy Forests.
Doc. Prof. Ing. Petr Kaštánek, PhD., the owner of the company, is a Czech scientist who specializes in the entire chain of research and use of natural bioactive substances. As part of the research projects he manages, new medicinal products based on active substances from hemp are developed for the treatment of inflammation, skin injuries and surgical wounds in the form of innovative nanoparticles or new active substances for cosmetics. Holder of the patent council and awards, e.g. Visionary 2016.

Own research and development
Our passion and expertise is in developing highly effective products that respect sustainability, environmental protection and user safety. The heart of our company is the laboratory, where we bring innovative ideas and products to the world.
Harmony of traditional healing and modern science and research
The development and production of products is carried out under the leadership of a leading Czech expert on bioactive substances, doc. Ing. Petr Kaštánek, PhD. based on a combination of knowledge of traditional natural healing practices and current scientific research carried out in state-supported research projects. We return to our roots - to the use of ecologically produced traditional and forgotten local herbs with the potential for use in dermatology, cosmetics and nutrition to produce our preparations.
Bioactive, highly usable ingredients
In our herbal dietary supplements and cosmetics, we use carefully prepared bioactive extracts. Where necessary for the organism's usability, we use bioactive substances formulated into highly absorbable liposomes, prepared using our own developed and patented NEOMICELLE TM and NeoCellTech TM processes.
Efficiency
Our products are based on a synergistic combination of active ingredients obtained by gentle extraction from plants and microalgae, often those that occur in extreme environments. This extreme origin is one of the reasons for their high effectiveness. Another is that we consistently use only standardized raw materials, where a high content of active ingredients is proven. We are only satisfied when our products are extreme: extremely effective.
Highest standards
There are large differences in the quality of natural, especially herbal active ingredients. The weather, growth and harvest during cultivation play a role here. NEOBOTANICS ® uses exclusively standardized raw materials. This means that the main active ingredient of the raw material must have the same controlled concentration and quality at all times.
Advanced know-how
NEOBOTANICS® products are developed by our own research teams and manufactured based on current scientific studies and the latest technologies. This allows high-quality natural active ingredients to be formulated in a gentle and innovative way, ensuring their positive synergistic effects in the product.
The result: highly complex recipes with herbal substances that reinforce each other in their effects.
Sustainable and ethical product
We have ABCert certification as a producer of organic food, in a number of products we use raw materials certified as VEGAN, RAW, BIO. When processing raw materials, we use gentle methods of green chemistry and apply internal principles of circular economy, using and recycling the maximum of raw material components. We have this experience thanks to the participation of our experts in the prestigious research centers BIOCIRTECH and BIORAF. Our company is family-owned, with a tradition of research in the field of natural substances in the second generation of academic staff.
Support for local producers
In production, herbs from our own eco-production and from proven Czech family farms are used, with strict quality and active ingredient content controls. In recent years, we have established research and production areas for a number of often forgotten traditional Czech herbs. For others, we use herbs from natural sources or from carefully selected growers and suppliers.
Vegetable capsules, suitable for vegans
In our products, we use, where technically possible, vegetable cellulose capsules, suitable for vegans, instead of cheaper gelatin capsules. We also avoid the tablet form, which is cheaper to produce, but uses a number of additives, such as amorphous silicon dioxide or magnesium stearate. We only use tablets when it is possible to produce them without these additives, as is the case with BIO PURE CHLORELLA or BIO SPIRULINA.
Free from GMO substances and ionizing radiation treatment
We consider genetically modified substances unsuitable for the production of food supplements and cosmetics and do not use them in our products. We also avoid treating raw materials with ionizing radiation, which can damage biologically active substances and deactivate enzymes.
Not tested on animals
When developing our cosmetic products, we use modern methods of testing substances in "in-vitro" tests; we never test on animals.
NO to unnecessary chemicals
In our dietary supplements, we minimize the use of unnecessary chemical additives such as artificial sweeteners, flavors, colors, and preservatives. These substances simplify production or extend the shelf life of products, but at the cost of ingesting substances that are unnatural for the body.
Certification and quality control
We manufacture cosmetics and dietary supplements while strictly adhering to good manufacturing practices and a carefully set critical control point system (HACCP). In our state-of-the-art laboratories, we manufacture products in both conventional and organic quality.
We select high-quality raw materials that meet our criteria of high standardized content of active ingredients and clear origin. During the process, we then control the entire production process. The result is safe, high-quality products that we assess for placing on the EU market. We control the quality of the products in our own operational laboratories and in external certified laboratories.
Transportation Czech Republic:
DPD:
-
DPD Classic 54 CZK
-
DPD Private (option to change date or address) 75 CZK
Zásilkovna:
-
Zásilkovna pick-up point or Z-box, selection after order completion 69.00 CZK
-
Zásilkovna delivery to address 99.00 CZK
Free shipping on orders over 2,000 CZK. Applies only to orders within the Czech Republic.
Payment options:
-
Online card payment (immediate transfer) free of charge
-
Bank transfer (transfer takes 1-2 days) free of charge
-
Cash on delivery (upon receipt) 30 CZK
Payment method providers: ComGate, Viva Payment
In the case of cashless payment, the purchase price is due within 7 days of the conclusion of the purchase agreement.
Delivery date of goods:
-
within 2-3 business days for online card payments and cash on delivery payments
-
within 2-4 business days for bank transfer payments
Shipping outside the Czech Republic:
Slovak Republic:
DPD:
-
DPD Classic 100 CZK (€4.00)
-
DPD Private (option to change date or address) 150 CZK (€7.00)
Packeta:
-
SK Packeta delivery to address 150 CZK (€6.00)
-
SK Packeta evening delivery to address 175 CZK (€7.00)
-
SK pick-up point or Z-box, selection after order completion 100 CZK (€4.00)
Payment options:
-
Bank transfer (transfer takes 1-2 days) free of charge
-
Online card payment (immediate transfer) free of charge
-
WARNING: Cash on delivery is not available for shipments outside the Czech Republic!
Delivery date of goods:
-
within 2-3 business days in case of payment by card
-
within 3-4 business days of the amount being credited to the account for bank transfer payments
For any questions regarding shipping or payment, please contact us at info@neobotanics.cz or call +420 776 187 414.
Neobotanics Anti-Wrinkle Skin Rejuvenator #1 anti-wrinkle serum with peptides, stem cells and hyaluronic acid 30 ml
A complete revolution in skin care! Discover the power of science and nature.
Discover the innovative Beauty line from Neobotanics for perfect skin.
Magazine editorial tip
Marianne.cz editorial test: The best skin serums that will rejuvenate your skin in a few days, tested serum: Neobotanics Anti-Wrinkle Skin Rejuvenator #1 from the Neobotanics brand, founded by Czech biochemist Petr Kaštánek, belongs in the evening skin care routine. It is highly concentrated and has a fast and strong effect against wrinkles.
Editor's review (50 years old): It feels like a light liquid that you don't even know is there. You feel as if you only have a little water on your face. I was very pleasantly surprised that the results were visible right after waking up. The product increases skin hydration, firmness and elasticity, making the skin beautifully rejuvenated.
You can try the effects of our skin serums and their combinations in a convenient test set.
Discovery set skin serum 4x4.5 ml

FOUR UNIQUE SKIN SERUMS backed by research into natural bioactive substances.
Two water serums marked #1:
- ANTI-WRINKLE SKIN REJUVENATOR #1 blue serum Marianne magazine editorial tip
- SKIN PERFECTOR #1 yellow serum recommended by VOGUE Czechoslovakia 2024 magazine
Two oil serums marked #2:
Interviews about individual serums with Doc. Ing. Petr Kaštánek, Ph.D., who is the founder of the Neobotanics brand and developed these products together with his team, can be found below.
ANTI-WRINKLE SKIN REJUVENATOR #1
Polypeptide and liposomal serum with stem cells
Highly concentrated aqueous liposomal serum with a unique peptide "delivery system", plant stem cell extracts, hyaluronic acid with a very small size and plant antioxidants from navel, ball, gardenia and janiba for a very fast and strong anti-wrinkle effect.
Do you want perfectly hydrated, soft and firm skin? Do you want to get rid of wrinkles and don't want to undergo any procedures?
Bet on the right effective ingredients offered by the revolutionary blue serum ANTI-WRINKLE SKIN REJUVENATOR #1.
Effects of ANTI-WRINKLE SKIN REJUVENATOR #1 Serum:
▪ Visibly reduces wrinkles by up to 67% in 28 days
▪ Increases skin elasticity by up to 106% in 6 weeks
▪ Increases collagen production and skin firmness
▪ Brightens
▪ Increases hydration
▪ Restores the skin microbiome
▪ Contains 5 biotechnological peptides
▪ stem cell extracts
▪ Liposomal active ingredients
▪ Very low molecular weight hyaluronic acid
Patented peptides eliminate wrinkles
The serum contains 5 specially selected and patented peptides that have undergone several studies, the percentages of the main results showed how much they contribute to the reduction of wrinkles per month of use. One of them showed up to 67% reduction of wrinkles in 28 days. This effectiveness is largely due to the special technology of the so-called cosmetic drone. One of the peptides used also gives the serum its characteristic blue color.
Beauty drone technology
This is a special "delivery system" that binds active ingredients (peptides) directly to the receptors of skin cells that are responsible for the production of collagen and collagen fibers. Thanks to the so-called "small drone", the active ingredients reach exactly the right place and thus their maximum use is achieved.
" This blue serum is unique in the combination and quantity of peptides and plant stem cell extracts used. It combines natural plant extracts and innovative biotechnological ingredients - e.g. deep sea microorganism ferment, stem cell extract, encapsulated peptides for complex anti-aging effects, etc. It is important that these bioactive substances used then activate the natural production of the skin's own molecules, such as collagen or the sirtuin enzyme. The effect is therefore more natural and long-lasting ," explains Doc. Ing. Petr Kaštánek, Ph.D. , scientist and director of research laboratories EcoFuel Laboratories and BIOCEN Laboratories, founder of the NEOBOTANICS cosmetic brands.
Based on research, extracts from lemon balm and heartwort stem cells were selected, which activate the natural defense mechanisms of skin cells and activate longevity enzymes that extend the lifespan of cells.
Special composition developed by Doc. Ing. Petr Kaštánek, Ph.D. , director of BIOCEN laboratories and founder of the NEOBOTANICS brand ™ , combines natural plant active ingredients and patented biotechnological innovative ingredients – 5 powerful anti-age peptides X50 Capsules ™ , Clodessin ™ , Argireline ™ Aplified, GCu11P ™ , NeoActine plant extracts ™ , stem cells by Resistem ™ and NeoCellTech ™ for comprehensive anti-aging effects, rapid wrinkle reduction and dramatically younger-looking skin.
The serum is quickly absorbed, does not leave a greasy layer on the skin and is designed to be combined with any skin care routine. It does not contain perfume or artificial colors.
Main active ingredients:
X50 Capsules ™ (Cu-Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate peptides) – Encapsulated copper peptides using breakthrough technology targeting the active ingredient to specific receptors of skin cells – fibroblasts. Stimulates the synthesis of collagen and elastin at the gene expression level and significantly reduces wrinkles on the entire surface of the skin. Hydrates and nourishes the skin, leaving it silkier and more elastic, leaving it younger, smoother, brighter and firmer. The study [1] demonstrated a significant reduction in wrinkles on the entire surface of the skin. The reduction in wrinkle reduction was 33%, with the best responder achieving a 67% reduction in the surface of fine wrinkles, a 46% reduction in the number of wrinkles and a 59% reduction in the length of wrinkles.
Clodessin ™ (sh-Nonapeptide-4) – is an active fragment of the hormone Klotho, which protects against premature aging caused by daily stress, pollutants and free radicals and makes the skin healthier and smoother. It prolongs the life of cells and natural defense mechanisms in cells. Administration of the "youth hormone" Klotho to the skin cell has a truly rejuvenating effect. In 6 weeks of application, the depth of wrinkles was reduced by 52%, skin elasticity was increased by 106% and pores were reduced by 16%. [2]
Argireline ™ Aplified (Acetyl Hexapeptide-8) – Penetrates deep into the skin, reducing fine lines and wrinkles at their source and minimizing the aging process in all layers of the skin. A safer topical alternative to botulinum toxin, effective in just 1 week. Suppresses muscle contraction and relaxation of facial muscles. Less stiff facial muscles are more relaxed, which is associated with a youthful appearance and fewer facial wrinkles. In a study of improving the appearance of facial wrinkles, the area changed by 11% in just 5 days and the depth of wrinkles decreased by up to 46.7% in 28 days. [3]
GCu11P ™ (Copper Tripeptide-1) - Increases collagen production and improves the appearance of skin, giving it a biological appearance. In a study, it reduced wrinkles by 29%, wrinkle area by 29%, and increased skin elasticity by 21.6%. [4]
HyActiv ™ (active hydrolyzed hyaluronic acid of very low molecular weight) penetrates even into the lowest layers of the skin, where it stimulates the production of the body's own endogenous hyaluronic and collagen and has a rejuvenating effect - helps smooth the skin, reduces wrinkles and pores and hydrates the skin. It also acts as a prebiotic, restoring the skin microbiome after its disruption. Supports the skin microflora.
Resist ™ - plant extract from Globularia cordifolia stem cells helps the skin create its own anti-aging defense system. It supports detoxification, prolongs cell life by stimulating the enzyme sertuin-1 and tissue regeneration.
Genipa americana Extract – extract from the fruit of the South American genipa with antioxidant effects.
Gardenia Florida fruit extract – gardenia extract has antioxidant and anti-aging effects on the skin.
Globularia Alypum Leaf Extract – an extract from the Globularia Alypum Leaf to soothe irritated skin and slow down its aging. It supports the reduction of skin reactivity.
NeoActine ™ Centella - an extract from the Asian centella for skin care.
[1] Study on 30 volunteers aged 35-70, 2 applications per day for 28 days.
[2] Study of 31 women aged 34-57, applied to the skin for 6 weeks.
[3] Study of 41 women aged 34-60.
[4] Study of 32 women aged 25-55, twice daily application for 56 days
USE and APPLICATION Neobotanics Beauty skin serums
A) TESTING PHASE – individual testing of serums (without combinations):
1. Cleansing the skin (makeup removing oil/milk/foam)
2. Skin toning (toner)
3. SERUM – apply a few drops and let dry , 1-2 times a day, preferably in the morning and evening
4. Cream/skin oil
In the testing phase, we recommend trying each serum alone for 2-3 days, i.e. not combining it with other serums.
The serum can be applied 1-2 times a day, preferably in the morning and evening.
B) REGULAR APPLICATION – combination of serums:
1. Cleansing the skin (makeup removing oil/milk/foam)
2. Skin toning (toner)
3. SERUM #1 - apply a few drops of water-based serum (#1) and let dry
4. SERUM #2 - apply a few drops of oil serum (#2) and let dry
5. Cream/skin oil
Drying time: water-based serum (#1) approx. 10 seconds, oil-based serum (#2) a little longer, approx. 30-60 seconds.
With regular application, serums can be combined, namely any water-based (#1) and oil-based serum (#2) , according to the current needs of the skin, see serum combinations.
Drying time: water-based serum (#1) approx. 10 seconds , oil-based serum (#2) approx. 30-60 seconds .
Quantity: only a few drops are needed, the serums are very concentrated. We recommend 1 drop on each cheek, another on the chin, nose and forehead, i.e. a total of about 5 drops.
How often to apply: 1-2 times a day , always in the evening, preferably in the morning and evening.
Notice:
We do not recommend layering the same type of serum twice = do not apply two water-based serums (#1 and #1) or two oil-based serums (#2 and #2) on top of each other. That is why the bottles are marked #1 and #2.
Using two of the same types of serums at the same time could disrupt the synergistic effect of the active ingredients or cause skin irritation due to an unnecessarily high amount of active ingredients.
SERUM COMBINATION:
Dry skin, deep wrinkles, loss of brightness and elasticity:
ANTI-WRINKLE SKIN REJUVENATOR #1 + INSTANT BEAUTY & RADIANCE #2
Dry skin, wrinkles, hyperpigmentation:
ANTI-WRINKLE SKIN REJUVENATOR #1 + YOUTH BOOSTER #2
Problematic skin, enlarged pores, acne, uneven skin tone:
SKIN PERFECTOR #1 + INSTANT BEAUTY & RADIANCE #2
Damaged skin, wrinkles, dehydration, hyperpigmentation:
SKIN PERFECTOR #1 + YOUTH BOOSTER #2
Do you want to learn about Anti-Age bioactive peptides that can help with wrinkles on your skin?
More about the article Anti-Age Bioactive Peptides: A Revolution in the Fight Against Wrinkles on our blog HERE .
The NEOBOTANICS® brand was created on the basis of scientific research into natural bioactive substances, led by Doc. Prof. Ing. Petr Kaštánek, PhD., in cooperation with major Czech scientific institutions and top doctors.
Research, development and production take place under the strictest conditions in the laboratories of our parent company BIOCEN laboratories and in the Science and Technology Park of the Applied Research Center Dobříš (CAVD) in the midst of the beautiful landscape of the Brdy Forests.
Doc. Prof. Ing. Petr Kaštánek, PhD., the owner of the company, is a Czech scientist who specializes in the entire chain of research and use of natural bioactive substances. As part of the research projects he manages, new medicinal products based on active substances from hemp are developed for the treatment of inflammation, skin injuries and surgical wounds in the form of innovative nanoparticles or new active substances for cosmetics. Holder of the patent council and awards, e.g. Visionary 2016.

Own research and development
Our passion and expertise is in developing highly effective products that respect sustainability, environmental protection and user safety. The heart of our company is the laboratory, where we bring innovative ideas and products to the world.
Harmony of traditional healing and modern science and research
The development and production of products is carried out under the leadership of a leading Czech expert on bioactive substances, doc. Ing. Petr Kaštánek, PhD. based on a combination of knowledge of traditional natural healing practices and current scientific research carried out in state-supported research projects. We return to our roots - to the use of ecologically produced traditional and forgotten local herbs with the potential for use in dermatology, cosmetics and nutrition to produce our preparations.
Bioactive, highly usable ingredients
In our herbal dietary supplements and cosmetics, we use carefully prepared bioactive extracts. Where necessary for the organism's usability, we use bioactive substances formulated into highly absorbable liposomes, prepared using our own developed and patented NEOMICELLE TM and NeoCellTech TM processes.
Efficiency
Our products are based on a synergistic combination of active ingredients obtained by gentle extraction from plants and microalgae, often those that occur in extreme environments. This extreme origin is one of the reasons for their high effectiveness. Another is that we consistently use only standardized raw materials, where a high content of active ingredients is proven. We are only satisfied when our products are extreme: extremely effective.
Highest standards
There are large differences in the quality of natural, especially herbal active ingredients. The weather, growth and harvest during cultivation play a role here. NEOBOTANICS ® uses exclusively standardized raw materials. This means that the main active ingredient of the raw material must have the same controlled concentration and quality at all times.
Advanced know-how
NEOBOTANICS® products are developed by our own research teams and manufactured based on current scientific studies and the latest technologies. This allows high-quality natural active ingredients to be formulated in a gentle and innovative way, ensuring their positive synergistic effects in the product.
The result: highly complex recipes with herbal substances that reinforce each other in their effects.
Sustainable and ethical product
We have ABCert certification as a producer of organic food, in a number of products we use raw materials certified as VEGAN, RAW, BIO. When processing raw materials, we use gentle methods of green chemistry and apply internal principles of circular economy, using and recycling the maximum of raw material components. We have this experience thanks to the participation of our experts in the prestigious research centers BIOCIRTECH and BIORAF. Our company is family-owned, with a tradition of research in the field of natural substances in the second generation of academic staff.
Support for local producers
In production, herbs from our own eco-production and from proven Czech family farms are used, with strict quality and active ingredient content controls. In recent years, we have established research and production areas for a number of often forgotten traditional Czech herbs. For others, we use herbs from natural sources or from carefully selected growers and suppliers.
Vegetable capsules, suitable for vegans
In our products, we use, where technically possible, vegetable cellulose capsules, suitable for vegans, instead of cheaper gelatin capsules. We also avoid the tablet form, which is cheaper to produce, but uses a number of additives, such as amorphous silicon dioxide or magnesium stearate. We only use tablets when it is possible to produce them without these additives, as is the case with BIO PURE CHLORELLA or BIO SPIRULINA.
Free from GMO substances and ionizing radiation treatment
We consider genetically modified substances unsuitable for the production of food supplements and cosmetics and do not use them in our products. We also avoid treating raw materials with ionizing radiation, which can damage biologically active substances and deactivate enzymes.
Not tested on animals
When developing our cosmetic products, we use modern methods of testing substances in "in-vitro" tests; we never test on animals.
NO to unnecessary chemicals
In our dietary supplements, we minimize the use of unnecessary chemical additives such as artificial sweeteners, flavors, colors, and preservatives. These substances simplify production or extend the shelf life of products, but at the cost of ingesting substances that are unnatural for the body.
Certification and quality control
We manufacture cosmetics and dietary supplements while strictly adhering to good manufacturing practices and a carefully set critical control point system (HACCP). In our state-of-the-art laboratories, we manufacture products in both conventional and organic quality.
We select high-quality raw materials that meet our criteria of high standardized content of active ingredients and clear origin. During the process, we then control the entire production process. The result is safe, high-quality products that we assess for placing on the EU market. We control the quality of the products in our own operational laboratories and in external certified laboratories.
Our knowledge. Your inspiration.
Discover articles full of tips, news, and interesting facts about natural cosmetics and a healthy lifestyle.
Collagen Peptides: Your Secret Weapon Against Cellulite
Collagen peptides have been proven to reduce cellulite, improve skin elasticity and increase dermis density after just 6 months.
Menopause: How to Manage Symptoms Naturally
Discover natural ways to manage menopause. Herbs, vitamins, omega-3s, and a healthy lifestyle will help for better well-being and balance.
Synthetic or natural vitamin C?
Vitamin C: natural vs. synthetic. Is it used the same way in the body? Find out if there are differences between natural sources and synthetic ascorbic acid supplements.