NEOLIPO D3+K2

NEOLIPO D3+K2 - Nano liposomal form of a high dose of vitamins D3 and K2, dietary supplement

• In the form of a liquid concentrate soluble in water
  
• Easy dosing in water, fruit juice, or cold or lukewarm tea
• Extremely strong formulation - the daily dose contains 500% of the recommended daily intake of vitamin D3 and 60% of K2
  
• Without dyes and aromas
  
• Made using NEOMICELLE™ technology, developed within research grant projects

Vitamin D contributes to:

• normal function of the immune system
• maintenance of normal bones and teeth
  
• maintaining normal muscle activity
• normal absorption/utilization of calcium and phosphorus
• normal blood calcium levels

Vitamin K contributes to:

• normal blood clotting
• maintenance of normal bone condition

The Czech population suffers from a lack of vitamin D. It is essential for strengthening immunity (1). Very few foods naturally contain or are enriched with vitamin D. People obtain it from exposure to sunlight, from a diet rich in fatty fish, or from medications and food supplements. It is estimated that up to 1 billion people worldwide may be vitamin D deficient. That is why it is absolutely necessary to supplement vitamin D either in a natural, natural form - the sun, fish, but also in an artificial form, i.e. medications and specialized food supplements.

Vitamin D deficiency mainly affects a large part of the elderly population, especially women who live in countries with a temperate climate, due to a reduced amount of vitamin D in the diet (the source is mainly the consumption of oily marine fish). The lowest seasonal concentration of the active form of vitamin D is usually observed during winter and spring. It is particularly alarming that more than 50% of post-menopausal women taking osteoporosis drugs have insufficient values ​​of the active form of vitamin D3 in their blood, as e.g. Boston University study (2). A study of outpatients in Denver showed vitamin D deficiency in even 74% of seniors aged 66-89 (3).

Vitamin K2 is an expensive substance, but research shows that it is very important for the human body (4), its source in food is mainly beef, yogurt and soft cheeses. However, its intake in a typical Central European diet may not be sufficient. Some of the vitamin K2 is also produced by bacteria naturally present in the human gut. However, their activity can be weakened in case of frequent use of antibiotics.

Expert studies show that it is advisable to combine vitamin D3 with vitamin K2. These synergistic (mutually reinforcing) effects of the simultaneous administration of vitamins D3 and K2 have been found in a number of studies (5-9).

¹ Grant WB, Lahore H, McDonnell SL, Baggerly CA, French CB, Aliano JL, Bhattoa HP. Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths. Nutrients. 2020 Apr 2;12(4):988.

² Holick MF. Vitamin D deficiency. N Engl J Med. 2007 Jul 19;357(3):266-81.

³ Linnebur SA, Vondracek SF, Vande Griend JP, Ruscin JM, McDermott MT. Prevalence of vitamin D insufficiency in elderly ambulatory outpatients in Denver, Colorado. Am J Geriatric Pharmacother. 2007 Mar;5(1):1-8.

⁴ Vitamin K as a Diet Supplement with Impact in Human Health: Current Evidence in Age-Related Diseases

Dina C. Simes, Carla SB Viegas, Nuna Araújo, Catarina Marreiros. Nutrients. 2020 Jan; 12(1): 138.

⁵ Goddek S. Vitamin D3 and K2 and their potential contribution to reducing the COVID-19 mortality rate. Int J Infect Dis. 2020 Oct;99:286-290.

⁶ Kidd PM. Vitamins D and K as pleiotropic nutrients: clinical importance to the skeletal and cardiovascular systems and preliminary evidence for synergy. Altern Med Rev. 2010 Sep;15(3):199-222.

⁷ Iwamoto J, Takeda T, Ichimura S. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis. J Orthop Sci. 2000;5(6):546-51.

⁸ Aguayo-Ruiz JI, García-Cobián TA, Pascoe-González S, Sánchez-Enríquez S, Llamas-Covarrubias IM, García-Iglesias T, López-Quintero A, Llamas-Covarrubias MA, Trujillo-Quiroz J, Rivera-Leon EA. . Effect of supplementation with vitamins D3 and K2 on undercarboxylated osteocalcin and insulin serum levels in patients with type 2 diabetes mellitus: a randomized, double-blind, clinical trial. Diabetol Metab Syndr. 2020 Aug 18;12:73.

⁹ Iwamoto J, Takeda T, Ichimura S. Treatment with vitamin D3 and/or vitamin K2 for postmenopausal osteoporosis. Keio J Med. 2003 Sep;52(3):147-50.